Extinguishing the flames of inflammation: retardant effect of chlorquinaldol on NLRP3-driven diseases

Extinguishing the flames of inflammation: retardant effect of chlorquinaldol on NLRP3-driven diseases

Abstract Background NLRP3 inflammasome immoderate activation results in the occurrence of various inflammatory diseases, but the clinic medications targeting NLRP3 inflammasome are still not available currently. The strategy of drug repurposing can reorient the direction of therapy, which is an indi...

Full description

Saved in:
Bibliographic Details
Main Authors: Zhilei Wang, Jingwen Liu, Yu Mou, Yuchen Li, Wenhao Liao, Menglin Yao, Ting Wang, Hongping Shen, Qin Sun, Jianyuan Tang
Format: Article
Language:English
Published: BMC 2024-12-01
Series:Molecular Medicine
Subjects:
Chlorquinaldol
NLRP3 inflammasome
Pyroptosis
Drug repurposing
Peritonitis
Colitis
Online Access:https://doi.org/10.1186/s10020-024-01016-1
Tags: Add Tag
No Tags, Be the first to tag this record!

Internet

https://doi.org/10.1186/s10020-024-01016-1

Similar Items