Transcriptomic and morphologic vascular aberrations underlying FCDIIb etiology

Transcriptomic and morphologic vascular aberrations underlying FCDIIb etiology

Abstract Focal cortical dysplasia type II (FCDII) is a major cause of drug-resistant epilepsy, but genetic factors explain only some cases, suggesting other mechanisms. In this study, we conduct a molecular analysis of brain lesions and adjacent areas in FCDIIb patients. By analyzing over 217,506 si...

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Main Authors: Chuantao Fang, Xiaodan Zhang, Lin Yang, Licheng Sun, Yujia Lu, Yi Liu, Jingjing Guo, Min Wang, Yanfeng Tan, Jinsen Zhang, Xin Gao, Li Zhu, Guoping Liu, Maozhi Ren, Jianbo Xiao, Fayong Zhang, Shaojie Ma, Rui Zhao, Xinyu Mei, Dashi Qi
Format: Article
Language:English
Published: Nature Portfolio 2025-04-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-025-58535-6
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https://doi.org/10.1038/s41467-025-58535-6

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