TACC3 enhances glycolysis in bladder cancer cells through inducing acetylation of c-Myc

Abstract The proliferation of bladder cancer (BC) cells is driven by metabolic reprogramming, marked by a glycolytic dependency to sustain uncontrolled growth. While Transforming Acidic Coiled-Coil Containing Protein 3 (TACC3) is known to promote BC progression and correlate with poor prognosis, the...

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Bibliographic Details
Main Authors: Zhirui Lin, Falian Liang, Gengde Hong, Xizhen Jiang, Qingling Zhang, Mengyao Wang
Format: Article
Language:English
Published: Nature Publishing Group 2025-04-01
Series:Cell Death and Disease
Online Access:https://doi.org/10.1038/s41419-025-07645-6
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