Time-restricted feeding attenuated hypertension-induced cardiac remodeling by modulating autophagy levels in spontaneously hypertensive rats

Time-restricted feeding attenuated hypertension-induced cardiac remodeling by modulating autophagy levels in spontaneously hypertensive rats

Abstract To investigate whether time-restricted feeding (TRF) can alleviate cardiac remodeling in spontaneously hypertensive rats (SHRs) by regulating autophagy levels. A 16-week TRF intervention was conducted on Wistar Kyoto (WKY) rats and SHRs, with dietary intake confined to the interval from 9:0...

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Bibliographic Details
Main Authors: Xin Yi, Razif Abas, Raja Abdul Wafy Raja Muhammad Rooshdi, Jie Yan, Canzhang Liu, Jiaxu An, Ummi Nadira Daut
Format: Article
Language:English
Published: Nature Portfolio 2025-05-01
Series:Scientific Reports
Subjects:
Time-restricted feeding
Hypertension
Cardiac remodelling
Autophagy
Spontaneously hypertensive rats
Online Access:https://doi.org/10.1038/s41598-025-01587-x
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https://doi.org/10.1038/s41598-025-01587-x

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