Escherichia coli type I toxin TisB exclusively controls proton depolarization following antibiotic induced DNA damage

Escherichia coli type I toxin TisB exclusively controls proton depolarization following antibiotic induced DNA damage

Abstract Bacterial toxin-antitoxin (TA) systems are genetic loci where the antitoxin gene product helps to control the expression or activity of the toxin gene product. Type I TA systems typically produce hydrophobic peptides that often localize to the inner membrane of bacteria. These amphipathic p...

Full description

Saved in:
Bibliographic Details
Main Authors: Tekle Airgecho Lobie, Charlotte Solum Krog, Kirsten Skarstad, Magnar Bjørås, James Alexander Booth
Format: Article
Language:English
Published: Nature Portfolio 2025-04-01
Series:Scientific Reports
Subjects:
TisB
Membrane depolarization
Type I toxin antitoxin systems
Antibiotics
DNA damage
E. coli
Online Access:https://doi.org/10.1038/s41598-025-96136-x
Tags: Add Tag
No Tags, Be the first to tag this record!

Internet

https://doi.org/10.1038/s41598-025-96136-x

Similar Items