Association of gut microbiota and immune gene expression with response to targeted therapy in BRAF mutated melanoma

Association of gut microbiota and immune gene expression with response to targeted therapy in BRAF mutated melanoma

Abstract Gut microbiota has been associated with carcinogenesis and immune regulation. While there is evidence supporting its influence on immunotherapy response in melanoma, its impact on BRAF/MEK-targeted therapy remains unexplored. This study assessed gut microbiota composition and immune-associa...

Full description

Saved in:
Bibliographic Details
Main Authors: Mora Guardamagna, Miguel-Angel Berciano-Guerrero, Rocío Lavado-Valenzuela, Édouard Auclin, Juan Luis Onieva-Zafra, Isaac Plaza-Andrades, Javier Oliver, Alicia Garrido-Aranda, Elisabeth Perez-Ruiz, Martina Álvarez, María Carmen Ocaña, María Isabel Queipo-Ortuño, Isabel Barragán, Antonio Rueda-Dominguez
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:Scientific Reports
Subjects:
Gut microbiota
Metastatic melanoma
Immune expression genes
Translational research
BRAF mutated melanoma
Immune system
Online Access:https://doi.org/10.1038/s41598-025-11054-2
Tags: Add Tag
No Tags, Be the first to tag this record!

Internet

https://doi.org/10.1038/s41598-025-11054-2

Similar Items