PGC7 regulates maternal mRNA translation via AKT1-YBX1 interactions in mouse oocytes

Abstract Timely and accurate translation of maternal mRNA is essential for oocyte maturation and early embryonic development. Previous studies have highlighted the importance of Primordial Germ cell 7 (PGC7) as a maternal factor in maintaining DNA methylation of maternally imprinted loci in zygotes....

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Bibliographic Details
Main Authors: Yingxiang Liu, Peiwen Feng, Xing Wei, Hongyu Xu, Mengying Yu, Lei Zhang, Weijie Hao, Zekun Guo
Format: Article
Language:English
Published: BMC 2024-12-01
Series:Cell Communication and Signaling
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Online Access:https://doi.org/10.1186/s12964-024-01976-1
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