Forsythiae Fructus attenuates cisplatin-induced cytotoxicity in IEC-6 ​cells and J774A.1 macrophages by inhibiting NLRP3/caspase-1/GSDMD mediated pyroptosis

Forsythiae Fructus attenuates cisplatin-induced cytotoxicity in IEC-6 ​cells and J774A.1 macrophages by inhibiting NLRP3/caspase-1/GSDMD mediated pyroptosis

Objective: Forsythiae Fructus (lian qiao in Chinese), the dried fruit of Forsythia suspensa (Thunb.) Vahl, is a commonly used traditional Chinese medicine known for its diverse biological activities, including antiemetic, anti-inflammatory, antioxidant, antiviral, and neuroprotective properties. Thi...

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Bibliographic Details
Main Authors: Binbin Ye, Ruifang Zhang, Yihong Xian, Xiuxiu Liao, Weijian Chen, Ke Nie
Format: Article
Language:English
Published: KeAi Communications Co., Ltd. 2023-10-01
Series:Journal of Holistic Integrative Pharmacy
Subjects:
Forsythiae fructus
Cisplatin
Cytotoxicity
NLRP3 inflammasome
Pyroptosis
Online Access:http://www.sciencedirect.com/science/article/pii/S2707368823000845
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