MicroRNA-669f-5p targeting deoxycytidinephosphate deaminase contributes to sevoflurane-induced cognitive impairments in aged mice via the TLR2/4–MyD88–NF-κB pathway

MicroRNA-669f-5p targeting deoxycytidinephosphate deaminase contributes to sevoflurane-induced cognitive impairments in aged mice via the TLR2/4–MyD88–NF-κB pathway

Background: Postoperative cognitive dysfunction (POCD) is a common complication associated with sevoflurane anaesthesia in the aged population. MicroRNAs have been implicated in sevoflurane-induced cognitive deficits; however, the role and underlying mechanism of microRNA (miR)-669f-5p remain unclea...

Full description

Saved in:
Bibliographic Details
Main Authors: Yuanping Zhong, Chao Zhang, Yuan Li, Dongqin Chen, Chunchun Tang, Xue Zheng, Zhaoqiong Zhu
Format: Article
Language:English
Published: Elsevier 2025-08-01
Series:Brain Research Bulletin
Subjects:
Postoperative cognitive dysfunction
Sevoflurane
MicroRNAs
Deoxycytidinephosphate deaminase
TLR2/4–MyD88–NF-κB signalling pathway
Online Access:http://www.sciencedirect.com/science/article/pii/S0361923025001935
Tags: Add Tag
No Tags, Be the first to tag this record!

Internet

http://www.sciencedirect.com/science/article/pii/S0361923025001935

Similar Items