An integrative analysis combining bioinformatics, network pharmacology and experimental methods identified key genes of EGCG targets in Nasopharyngeal Carcinoma

An integrative analysis combining bioinformatics, network pharmacology and experimental methods identified key genes of EGCG targets in Nasopharyngeal Carcinoma

Abstract Background Epigallocatechin gallate (EGCG), a frequently studied catechin in green tea, has been shown to be involved in the antiproliferation and apoptosis of human Nasopharyngeal carcinoma (NPC) cells. However, the pharmacological targets and mechanism by which EGCG can combat NPC patient...

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Bibliographic Details
Main Authors: Yuhang Yang, Wenqi Luo, Zhang Feng, Xiaoyu Chen, Jinqing Li, Long Zuo, Meijiao Duan, Xiaosong He, Wenhua Wang, Feng He, Fangxian Liu
Format: Article
Language:English
Published: Springer 2025-05-01
Series:Discover Oncology
Subjects:
EGCG
Nasopharyngeal carcinoma
Network pharmacology
Bioinformatics
Prognostic signature
Tumor microenvironment
Online Access:https://doi.org/10.1007/s12672-025-02365-x
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https://doi.org/10.1007/s12672-025-02365-x

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