Biomechanical control of vascular morphogenesis by the surrounding stiffness

Abstract Sprouting angiogenesis is a form of morphogenesis which expands vascular networks from preexisting networks. However, the precise mechanism governing efficient branch elongation driven by directional movement of endothelial cells (ECs), while the lumen develops under the influence of blood...

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Bibliographic Details
Main Authors: Yasuyuki Hanada, Semanti Halder, Yuichiro Arima, Misato Haruta, Honami Ogoh, Shuntaro Ogura, Yukihiko Shiraki, Sota Nakano, Yuka Ozeki, Shigetomo Fukuhara, Akiyoshi Uemura, Toyoaki Murohara, Koichi Nishiyama
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-025-61804-z
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