SARS-CoV-2 ORF3a drives dynamic dense body formation for optimal viral infectivity
Abstract SARS-CoV-2 hijacks multiple organelles for virion assembly, of which the mechanisms have not been fully understood. Here, we identified a SARS-CoV-2-driven membrane structure named the 3a dense body (3DB). 3DBs are unusual electron-dense and dynamic structures driven by the accessory protei...
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| Main Authors: | Stella Hartmann, Lisa Radochonski, Chengjin Ye, Luis Martinez-Sobrido, Jueqi Chen |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2025-05-01
|
| Series: | Nature Communications |
| Online Access: | https://doi.org/10.1038/s41467-025-59475-x |
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