Single-cell transcriptome profiling reveals dynamic cell populations and immune infiltration in cerebral cavernous malformation

Single-cell transcriptome profiling reveals dynamic cell populations and immune infiltration in cerebral cavernous malformation

IntroductionThe cellular subpopulations and signaling pathways in the pathological tissues of cerebral cavernous malformation (CCM) remain incompletely understood. To gain a deeper understanding of the pathogenesis of CCM, we aimed to comprehensively map the cellular subpopulations and signaling pat...

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Bibliographic Details
Main Authors: Zhiguang Han, Chengxu Lei, Zhenyu Zhou, Yutong Liu, Yuanli Zhao, Shihao He
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-05-01
Series:Frontiers in Immunology
Subjects:
cerebral cavernous malformation
single-cell RNA sequencing
multiplex fluorescent immunohistochemistry
cell populations
immune infiltration
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2025.1592343/full
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https://www.frontiersin.org/articles/10.3389/fimmu.2025.1592343/full

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