Endoplasmic Reticulum Stress and Lipid Metabolism: Mechanisms and Therapeutic Potential

The endoplasmic reticulum (ER) plays a crucial role in protein folding, assembly, and secretion. Disruption of ER homeostasis may lead to accumulation of misfolded or unfolded proteins in the ER lumen, a condition referred to as ER stress. In response to ER stress, a signal transduction pathway know...

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Bibliographic Details
Main Authors: Sana Basseri, Richard C. Austin
Format: Article
Language:English
Published: Wiley 2012-01-01
Series:Biochemistry Research International
Online Access:http://dx.doi.org/10.1155/2012/841362
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