Cross-sectional and longitudinal quantification of total white matter perivascular space volume fraction in Dutch-type Cerebral Amyloid Angiopathy

Cross-sectional and longitudinal quantification of total white matter perivascular space volume fraction in Dutch-type Cerebral Amyloid Angiopathy

Enlarged perivascular spaces (PVS) in the centrum semiovale are an important marker of Cerebral Amyloid Angiopathy (CAA) and are thought to reflect brain clearance dysfunction. However, the current golden standard for assessing PVS is limited to a unilateral, single slice, qualitative analysis, whic...

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Main Authors: Manon R. Schipper, Thijs W. van Harten, Arie-Tjerk Razoux-Schultz, Kanishk Kaushik, Lydiane Hirschler, Sabine Voigt, Ingeborg Rasing, Emma A. Koemans, Rosemarie van Dort, Reinier G.J. van der Zwet, Sanne E. Schriemer, Erik W. van Zwet, Jeroen van der Grond, Mark A. van Buchem, Steven M. Greenberg, Marieke J.H. Wermer, Matthias J.P. van Osch, Marianne A.A. van Walderveen, Sanneke van Rooden
Format: Article
Language:English
Published: Elsevier 2025-01-01
Series:NeuroImage: Clinical
Subjects:
Perivascular spaces
Brain clearance
Amyloid-β
Cerebral amyloid angiopathy
Dutch-type cerebral amyloid angiopathy
Hereditary cerebral hemorrhage with amyloidosis Dutch-type
Online Access:http://www.sciencedirect.com/science/article/pii/S2213158225000488
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