Post-resuscitation blood pressure management: Effects of different MAP targets on cerebral perfusion and inflammation in a porcine model

Post-resuscitation blood pressure management: Effects of different MAP targets on cerebral perfusion and inflammation in a porcine model

Background: Post-resuscitation care aims to optimize organ perfusion while mitigating reperfusion injury following the return of spontaneous circulation (ROSC). However, the optimal mean arterial pressure (MAP) target for neuroprotection remains undefined. This study investigates the impact of diffe...

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Main Authors: Andreas García Bardon, Jens Kamuf, Alexander Ziebart, Christian Breit, Karsten Sommer, Erik K. Hartmann, Maren Paul, Tanghua Liu, Petra Leukel, Victoria Albertsmeier, Isra Hale, Robert F. Kelm, Christoph Jänig, Laura Maria Schreiber, Willi Schmidbauer, Serge C. Thal
Format: Article
Language:English
Published: Elsevier 2025-05-01
Series:Resuscitation Plus
Subjects:
Post-resuscitation care
Mean arterial pressure (MAP)
Cerebral perfusion
Reperfusion injury
Inflammation
Magnetic resonance imaging (MRI)
Online Access:http://www.sciencedirect.com/science/article/pii/S2666520425000670
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