Medium from human iPSC-derived primitive macrophages promotes adult cardiomyocyte proliferation and cardiac regeneration

Medium from human iPSC-derived primitive macrophages promotes adult cardiomyocyte proliferation and cardiac regeneration

Abstract Heart injury has been characterized by the irreversible loss of cardiomyocytes comprising the contractile tissues of the heart and thus strategies enabling adult cardiomyocyte proliferation are highly desired for treating various heart diseases. Here, we test the ability of human induced pl...

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Main Authors: Yi Xiao, Hao Zhang, Xu Liu, Pengfei Xu, Heng Du, Jiawan Wang, Jianghua Shen, Yujing Li, Yuhan Wang, Chuting He, Haiping Feng, Jingfang Liu, Yanan Zhou, Siqi Liu, Zeyu Gao, Jingyi Zang, Jinmiao Bi, Tie-Shan Tang, Qi Gu, Tuo Wei, Jun Wang, Moshi Song
Format: Article
Language:English
Published: Nature Portfolio 2025-03-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-025-58301-8
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https://doi.org/10.1038/s41467-025-58301-8

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