Effects of Neoadjuvant Denosumab on Radiological and Histological Responses in Patients Undergoing En Bloc Resection for Giant Cell Tumor of Bone: A Systematic Review

Effects of Neoadjuvant Denosumab on Radiological and Histological Responses in Patients Undergoing En Bloc Resection for Giant Cell Tumor of Bone: A Systematic Review

Background: Giant cell tumor of bone (GCTB) is a rare primary bone tumor. The standard treatment is en bloc resection, which can be challenging due to tumor size or location. Denosumab, a monoclonal antibody, has emerged as a promising neoadjuvant therapy for GCTB, potentially facilitating surgical...

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Bibliographic Details
Main Authors: Hendra Aditama, Yo Tendy Pratama, Dhanan Prastanika S, Dita Anggara K, Rhyan Dharma S
Format: Article
Language:English
Published: Universitas Airlangga 2024-10-01
Series:Journal Orthopaedi and Traumatology Surabaya
Subjects:
cancer
denosumab
giant cell tumor of bone
human and medicine
Online Access:https://e-journal.unair.ac.id/JOINTS/article/view/50915
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