Alginate–Gelatin Hydrogel Scaffold Model for Hypoxia Induction in Glioblastoma Embedded Spheroids

Alginate–Gelatin Hydrogel Scaffold Model for Hypoxia Induction in Glioblastoma Embedded Spheroids

Glioblastoma (GBM) is a highly aggressive and malignant brain tumor, characterized by hypoxia in its microenvironment, which drives its growth and resistance to treatments. Hypoxia-inducible factor 1 (HIF-1) plays a central role in GBM progression by regulating cellular adaptation to low oxygen avai...

Full description

Saved in:
Bibliographic Details
Main Authors: Janette del Rocío Aguilera-Marquez, Alejandro Manzanares-Guzmán, Lorena García-Uriostegui, Alejandro A. Canales-Aguirre, Tanya A. Camacho-Villegas, Pavel H. Lugo-Fabres
Format: Article
Language:English
Published: MDPI AG 2025-04-01
Series:Gels
Subjects:
glioblastoma
3D culture
scaffold-based spheroid model
hypoxia
HIF-1 α
Online Access:https://www.mdpi.com/2310-2861/11/4/263
Tags: Add Tag
No Tags, Be the first to tag this record!

Internet

https://www.mdpi.com/2310-2861/11/4/263

Similar Items