Pathologic complete response and breast cancer survival post-neoadjuvant chemotherapy: A systematic review and meta-analysis of real-world data

Pathologic complete response and breast cancer survival post-neoadjuvant chemotherapy: A systematic review and meta-analysis of real-world data

Breast cancer is a leading cause of cancer-related mortality worldwide, and neoadjuvant chemotherapy (NAC) plays a pivotal role in its management by reducing tumor size, enabling breast-conserving surgery, and improving survival outcomes. Achieving pathologic complete response (pCR) is strongly asso...

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Main Authors: Marcelo Antonini, André Mattar, Thais Melo Pereira, Ludmila Lemos Oliveira, Marina Diógenes Teixeira, Andressa Gonçalves Amorim, Odair Ferraro, Larissa Chrispim de Oliveira, Marcellus do Nascimento Moreira Ramos, Francisco Pimentel Cavalcante, Felipe Zerwes, Marcelo Madeira, Leonardo Ribeiro Soares, Eduardo Camargo Millen, Antonio Luiz Frasson, Fabricio Palermo Brenelli, Gil Facina, Rogerio Fenile, Renata Arakelian, Ruffo de Freitas Júnior, Marcela Bonalumi dos Santos, Henrique Lima Couto, Luiz Henrique Gebrim
Format: Article
Language:English
Published: Elsevier 2025-05-01
Series:Heliyon
Subjects:
Neoadjuvant chemotherapy
Pathologic complete response
Breast cancer
Survival
Disease-free survival
HER2-Positive
Online Access:http://www.sciencedirect.com/science/article/pii/S2405844025014501
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