Multiple routes for non-physiological l-threonine uptake in Escherichia coli K-12

Multiple routes for non-physiological l-threonine uptake in Escherichia coli K-12

In this study, we identified eight multicopy suppressors (yhjE, sdaC, ydgI, alaE, ychE, yqeG, proP, and yjeM) and three distinct classes of chromosomal mutations (lrp, marC, and cycA) capable of complementing the growth defect caused by threonine uptake deficiency in the sstT tdcC livKHMGF brnQ thrP...

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Main Authors: Dmitrii M. Bubnov, Andrey A. Khozov, Tatiana V. Vybornaya, Agnessa A. Stepanova, Sergey V. Molev, Olga E. Melkina, Gennadii A. Badun, Maria G. Chernysheva, Ilia A. Skob, Alexander I. Netrusov, Sergey P. Sineoky
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-04-01
Series:Frontiers in Microbiology
Subjects:
Escherichia coli
l-threonine uptake
transmembrane transport
amino acid transporter
membrane proteins
Online Access:https://www.frontiersin.org/articles/10.3389/fmicb.2025.1579813/full
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https://www.frontiersin.org/articles/10.3389/fmicb.2025.1579813/full

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