Determination of Valdecoxib in Human Plasma Using Reverse Phase HPLC

An RP-HPLC analytical method for estimation of valdecoxib in human plasma was developed and validated. Protein precipitation and valdecoxib extraction from plasma (200 μL) was carried out by adding 800 μL perchloric acid (5%, v/v in water) containing nimesulide as the internal standard followed by v...

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Bibliographic Details
Main Authors: Prafulla Kumar Sahu, K. Ravi Sankar, M. Mathrusri Annapurna
Format: Article
Language:English
Published: Wiley 2011-01-01
Series:E-Journal of Chemistry
Online Access:http://dx.doi.org/10.1155/2011/148938
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