FliA regulates the antibacterial activity of plantaricin BM-1 against Escherichia coli K-12 through the LuxS/AI-2 quorum-sensing-mediated biofilm formation

FliA regulates the antibacterial activity of plantaricin BM-1 against Escherichia coli K-12 through the LuxS/AI-2 quorum-sensing-mediated biofilm formation

IntroductionPlantaricin BM-1 is a class IIa bacteriocin active against Escherichia coli. However, the mode of action of class IIa bacteriocins against gram-negative bacteria remains unclear. In this study, the regulatory role of sigma factor FliA (σ28) in the antibacterial mechanism of plantaricin B...

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Bibliographic Details
Main Authors: Shichun Wang, Xiaodong Song, Xuan Zheng, Congyang Cheng, Junhua Jin, Yuanhong Xie, Hongxing Zhang
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-06-01
Series:Frontiers in Microbiology
Subjects:
class IIa bacteriocins
Escherichia coli
FliA
biofilm formation
transcriptome
Online Access:https://www.frontiersin.org/articles/10.3389/fmicb.2025.1606567/full
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https://www.frontiersin.org/articles/10.3389/fmicb.2025.1606567/full

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