Precocious Puberty and Benign Variants in Female Children: Etiology, Diagnostic Challenges, and Clinical Management

Precocious Puberty and Benign Variants in Female Children: Etiology, Diagnostic Challenges, and Clinical Management

Precocious puberty, defined as the onset of secondary sexual characteristics before age 8 in girls, presents a diagnostic challenge in distinguishing between normal variants and pathological conditions requiring intervention. Central precocious puberty (CPP) results from early activation of the hypo...

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Bibliographic Details
Main Authors: Roberto Paparella, Arianna Bei, Lorenzo Brilli, Vittorio Maglione, Francesca Tarani, Marcello Niceta, Ida Pucarelli, Luigi Tarani
Format: Article
Language:English
Published: MDPI AG 2025-06-01
Series:Endocrines
Subjects:
precocious puberty
premature thelarche
premature adrenarche
children
female
Online Access:https://www.mdpi.com/2673-396X/6/2/29
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