Changed genome heterochromatinization upon prolonged activation of the Raf/ERK signaling pathway.

The Raf/ERK (Extracellular Signal Regulated Kinase) signal transduction pathway controls numerous cellular processes, including growth, differentiation, cellular transformation and senescence. ERK activation is thought to involve complex spatial and temporal regulation, to achieve a high degree of s...

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Bibliographic Details
Main Authors: Catherine Martin, Songbi Chen, Daniela Heilos, Guido Sauer, Jessica Hunt, Alexander George Shaw, Paul Francis George Sims, Dean Andrew Jackson, Josip Lovrić
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-10-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0013322&type=printable
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