Stepwise strategy for generating human trophoblast stem-like cells from embryonic stem cells reveals specific role of TFAP2C in acquiring self-renewability
Abstract Human trophoblast stem cells (TSCs) can self-renew and differentiate into major trophoblast lineages. Although TSC-like cells can be derived from both naïve and primed pluripotent stem cells (PSCs), the mechanisms governing the conversion of PSCs into a TSC state remain only partially under...
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| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2025-05-01
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| Series: | Scientific Reports |
| Subjects: | |
| Online Access: | https://doi.org/10.1038/s41598-025-03830-x |
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