Understanding the Mechanism of Bent DNA Amplifying Sensors Using All-Atom Molecular Dynamics Simulations

Bent DNA amplifying sensors were recently developed to amplify and quantify the interactions of DNA with various salts and molecules. However, a thorough quantitative understanding of their mechanism is missing. Here, using all-atom molecular dynamics (MD) simulations, we investigate the behavior an...

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Bibliographic Details
Main Authors: Kaitlin Bullard, Deborah Okyere, Shelbi J. Foster, Asmaa A. Sadoon, Jiali Li, Jingyi Chen, Yong Wang
Format: Article
Language:English
Published: MDPI AG 2025-04-01
Series:Biosensors
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Online Access:https://www.mdpi.com/2079-6374/15/5/272
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