Quantitative adverse outcome pathway modeling for cigarette smoke-inducible airway mucus hypersecretion. Part 2: Bayesian network modeling for probabilistic risk estimation

The development of in vitro tests that reproduce real-world situations is crucial for toxicity- and disease-risk assessment without animal testing. Because signs and symptoms of health concerns can be complex, it is helpful to create a simplified representation of such manifestations using a concept...

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Bibliographic Details
Main Authors: Shigeaki Ito, Sakuya Ichikawa, Risa Matsumoto, Shugo Muratani, Keigo Sano, Akina Mori, Kazuo Erami
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-05-01
Series:Frontiers in Toxicology
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Online Access:https://www.frontiersin.org/articles/10.3389/ftox.2025.1564864/full
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