Molecular cloning and characterization of the human ErbB4 gene: identification of novel splice isoforms in the developing and adult brain.

ErbB4 is a growth factor receptor tyrosine kinase essential for neurodevelopment. Genetic variation in ErbB4 is associated with schizophrenia and risk-associated polymorphisms predict overexpression of ErbB4 CYT-1 isoforms in the brain in the disorder. The molecular mechanism of association is uncle...

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Bibliographic Details
Main Authors: Wei Tan, Michael Dean, Amanda J Law
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-09-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0012924&type=printable
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