LILRB2 blockade facilitates macrophage repolarization and enhances T cell-mediated antitumor immunity

LILRB2 blockade facilitates macrophage repolarization and enhances T cell-mediated antitumor immunity

Background Immune checkpoint inhibitors have revolutionized the treatment of solid tumors, enhancing clinical outcomes by releasing T cells from inhibitory effects of receptors like programmed cell death protein 1 (PD-1). Despite these advancements, achieving durable antitumor responses remains chal...

Full description

Saved in:
Bibliographic Details
Main Authors: D Gareth Rees, Robert W Wilkinson, Mark Cobbold, Georgina Bowyer, Kathy Mulgrew, Simon J Dovedi, Fernanda Arnaldez, Des C Jones, Lorraine Irving, Marcin Wolny, Seraina Blümli, Stacy Pryts, Michael Kierny, Sonja Hess, Rebecca Dudley, Elisavet I Chatzopoulou, Shreya Ahuja, Alan M Sandercock, Saravanan Rajan, Reena Varkey, Andrew Kayserian, Saly Songvilay, Kamila Bienkowska, Matthew S Glover
Format: Article
Language:English
Published: BMJ Publishing Group 2025-04-01
Series:Journal for ImmunoTherapy of Cancer
Online Access:https://jitc.bmj.com/content/13/4/e010012.full
Tags: Add Tag
No Tags, Be the first to tag this record!

Internet

https://jitc.bmj.com/content/13/4/e010012.full

Similar Items