Nanotechnology-Driven Strategy Against SARS-CoV-2: Pluronic F127-Based Nanomicelles with or Without Atazanavir Reduce Viral Replication in Calu-3 Cells

Nanotechnology-Driven Strategy Against SARS-CoV-2: Pluronic F127-Based Nanomicelles with or Without Atazanavir Reduce Viral Replication in Calu-3 Cells

Despite extensive efforts, no highly effective antiviral molecule exists for treating moderate and severe COVID-19. Nanotechnology has emerged as a promising approach for developing novel drug delivery systems to enhance antiviral efficacy. Among these, polymeric nanomicelles improve the solubility,...

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Bibliographic Details
Main Authors: Eduardo Ricci-Junior, Alice Santos Rosa, Tatielle do Nascimento, Ralph Santos-Oliveira, Marcos Alexandre Nunes da Silva, Debora Ferreira Barreto-Vieira, Luísa Tozatto Batista, Giovanna Barbosa da Conceição, Tayane Alvites Nunes Quintão, Vivian Neuza Santos Ferreira, Milene Dias Miranda
Format: Article
Language:English
Published: MDPI AG 2025-04-01
Series:Viruses
Subjects:
SARS-CoV-2
Calu-3 cells
antiviral activity
nanotechnology
polymeric micelles
poloxamer
Online Access:https://www.mdpi.com/1999-4915/17/4/518
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