SREBP2-dependent lipid droplet formation enhances viral replication and deteriorates lung injury in mice following IAV infection

SREBP2-dependent lipid droplet formation enhances viral replication and deteriorates lung injury in mice following IAV infection

Influenza A virus (IAV) is a significant zoonotic pathogen that poses a considerable challenge to public health due to its continuous mutations. Lipid droplets (LDs) have been shown to play an important role in the process of several viral infections. However, their role in IAV infection remains unc...

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Bibliographic Details
Main Authors: Xinsen Li, Lu Li, Jijing Tian, Ruijing Su, Jiali Sun, Yuli Li, Lige Wang, Hongye Zhou, Shuhan Sha, Jin Xiao, Hong Dong, Caiyun Huo, Yanxin Hu, Hanchun Yang
Format: Article
Language:English
Published: Taylor & Francis Group 2025-12-01
Series:Emerging Microbes and Infections
Subjects:
Influenza A virus
lipid droplets
SREBP2
viral replication
lung injury
Online Access:https://www.tandfonline.com/doi/10.1080/22221751.2025.2470371
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https://www.tandfonline.com/doi/10.1080/22221751.2025.2470371

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