Tandem reductive amination and deuteration over a phosphorus-modified iron center

Abstract Deuterated amines are key building blocks for drug synthesis and the identification of metabolites of new pharmaceuticals, which drives the search for general, efficient, and widely applicable methods for the selective synthesis of such compounds. Here, we describe a multifunctional phospho...

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Bibliographic Details
Main Authors: Haifeng Qi, Yueyue Jiao, Jianglin Duan, Nicholas F. Dummer, Bin Zhang, Yujing Ren, Stuart H. Taylor, Yong Qin, Kathrin Junge, Haijun Jiao, Graham J. Hutchings, Matthias Beller
Format: Article
Language:English
Published: Nature Portfolio 2025-02-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-024-55722-9
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