Reduced T and NK Cell Activity in Glioblastoma Patients Correlates with TIM-3 and BAT3 Dysregulation

Inhibitory receptors are critical for regulating immune cell function. In cancer, these receptors are often over-expressed on the cell surface of T and NK cells, leading to reduced anti-tumor activity. Here, through the analysis of 11 commonly studied checkpoint and inhibitory receptors, we discern...

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Main Authors: Farah Ahmady, Peter Curpen, Louis Perriman, Adilson Fonseca Teixeira, Siqi Wu, Hong-Jian Zhu, Arpita Poddar, Aparna Jayachandran, George Kannourakis, Rodney B. Luwor
Format: Article
Language:English
Published: MDPI AG 2024-10-01
Series:Cells
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Online Access:https://www.mdpi.com/2073-4409/13/21/1777
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