Discovery of Novel Tofacitinib–ADTOH Molecular Hybridization Derivatives for the Treatment of Ulcerative Colitis

The treatment of ulcerative colitis (UC) has been a major medical challenge due to the lack of safe and effective drugs. Molecular hybridization is a promising strategy for the development of drugs with pleiotropic activity, which has been demonstrated in a wide range of diseases. Tofacitinib has ex...

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Bibliographic Details
Main Authors: Yi Mou, Shuai Wen, Yan Wang, Yao Zhao, Ying-Ping Li, Hong-Kai Sha, Li-Juan Gui, Zheng-Yu Jiang, Xiang-Ming Xu
Format: Article
Language:English
Published: MDPI AG 2025-03-01
Series:Antioxidants
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Online Access:https://www.mdpi.com/2076-3921/14/3/325
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