Chronic metabolic stress impairs lymphatic contractility via activation of KATP channels in a mouse model of Type-2 diabetes

IntroductionChronic metabolic stress is a common underlying factor of multiple diseases, including obesity, type II diabetes, and metabolic syndrome. Lymphatic dysfunction, including valve defects, impaired contractile activity, and hyperpermeability, is also associated with these same diseases. We...

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Bibliographic Details
Main Authors: Jorge A. Castorena-Gonzalez, Hae Jin Kim, Michael J. Davis
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-04-01
Series:Frontiers in Physiology
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Online Access:https://www.frontiersin.org/articles/10.3389/fphys.2025.1558763/full
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