Cooperation between coagulase and von willebrand factor binding protein in Staphylococcus aureus fibrin pseudocapsule formation

The major human pathogen Staphylococcus aureus forms biofilms comprising of a fibrin network that increases attachment to surfaces and shields bacteria from the immune system. It secretes two coagulases, Coagulase (Coa) and von Willebrand factor binding protein (vWbp), which hijack the host coagulat...

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Bibliographic Details
Main Authors: Dominique C.S. Evans, Amanda B. Khamas, Alex Payne-Dwyer, Adam J.M. Wollman, Kristian S. Rasmussen, Janne K. Klitgaard, Birgitte Kallipolitis, Mark C. Leake, Rikke L. Meyer
Format: Article
Language:English
Published: Elsevier 2024-12-01
Series:Biofilm
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Online Access:http://www.sciencedirect.com/science/article/pii/S2590207524000583
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