The lactylation-macrophage interplay: implications for gastrointestinal disease therapeutics
Lactate, a key metabolic byproduct of the Warburg effect, has lately been recognized as a regulator of histone lysine lactylation, a unique post-translational modification that plays a crucial role in essential biological processes, including the regulation of gene transcription. Lactylation plays a...
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| Main Authors: | Xinzhen Che, Yixin Zhang, Xiqi Chen, Guangdong Xie, Jinling Li, Chengchao Xu, Chunhua Zhang, Yong Zhu, Xinyu Yang |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Frontiers Media S.A.
2025-07-01
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| Series: | Frontiers in Immunology |
| Subjects: | |
| Online Access: | https://www.frontiersin.org/articles/10.3389/fimmu.2025.1608115/full |
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