Bioconjugated clicked chitosan/alginate nanocarriers with trastuzumab: Unlocking curcumin's potential in targeting breast cancer

Bioconjugated clicked chitosan/alginate nanocarriers with trastuzumab: Unlocking curcumin's potential in targeting breast cancer

Curcumin (Cur) has shown potential anticancer effects against various cancers, including colorectal and breast cancers. The aim of this study was to develop nanocarriers (NCs) bioconjugated with trastuzumab (Tras) using click reactions. Chitosan-maleimide (CHI-Mal) and thiolated alginate (SH-ALG) we...

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Bibliographic Details
Main Authors: Chaiyakarn Pornpitchanarong, Yin Yin Myat, Nitjawan Sahatsapan, Supusson Pengnam, Theerasak Rojanarata, Praneet Opanasopit, Tanasait Ngawhirunpat, Prasopchai Patrojanasophon
Format: Article
Language:English
Published: Elsevier 2024-12-01
Series:Carbohydrate Polymer Technologies and Applications
Subjects:
Thiol-maleimide click reaction
Chitosan-maleimide
Thiolated alginate
Cancer
Nanocarriers
Curcumin
Online Access:http://www.sciencedirect.com/science/article/pii/S2666893924001439
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http://www.sciencedirect.com/science/article/pii/S2666893924001439

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