Optimization and transfer of robust primary drying protocols for biopharmaceuticals through lyophilization process modeling
Abstract Lyophilization, or freeze-drying, is a widespread process for stabilizing (bio)pharmaceutical products. The primary drying phase is resource-intensive, making its optimization a focal point for improving economic and environmental sustainability. Mechanistic modeling of the primary drying p...
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| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
SpringerOpen
2025-06-01
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| Series: | AAPS Open |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s41120-025-00115-5 |
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