Reviving hope: unlocking pancreatic islet immortality by optimizing a trehalose-based cryopreservation media and cell-penetrating peptide

Abstract Background Diabetes mellitus remains a pervasive global health concern, urging a deeper exploration of islet transplantation as a potential enduring solution. The efficacy of this therapeutic approach pivots on the precision of cryopreservation techniques, ensuring both the viability and ac...

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Bibliographic Details
Main Authors: Zakieh Samsonchi, Roshanak Amirian, Lobat Tayebi, Hossein Derakhshankhah, Zhila Izadi, Ensiyeh Hajizadeh-Saffar
Format: Article
Language:English
Published: BMC 2025-03-01
Series:Stem Cell Research & Therapy
Online Access:https://doi.org/10.1186/s13287-025-04168-x
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