Human umbilical cord mesenchymal stem cells improve disease characterization of Sjogren's syndrome in NOD mice through regulation of gut microbiota and Treg/Th17 cellular immunity

Human umbilical cord mesenchymal stem cells improve disease characterization of Sjogren's syndrome in NOD mice through regulation of gut microbiota and Treg/Th17 cellular immunity

Abstract Background For the unclear pathogenesis of Sjogren's syndrome (SS), further exploration is necessary. Mesenchymal stem cells (MSCs) and derived exosomes (MSCs‐exo) have exhibited promising results in treating SS. Object This study aimed to investigate the effect and mechanism of human...

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Bibliographic Details
Main Authors: Yao Zou, Wei Xiao, Dongzhou Liu, Xianyao Li, Lihua Li, Lijuan Peng, Ying Xiong, Haina Gan, Xiang Ren
Format: Article
Language:English
Published: Wiley 2024-01-01
Series:Immunity, Inflammation and Disease
Subjects:
gut microbiota
human umbilical cord mesenchymal stem cells
Sjogren's syndrome
Treg/Th17
Online Access:https://doi.org/10.1002/iid3.1139
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https://doi.org/10.1002/iid3.1139

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