Maternal e-cigarette exposure alters DNA methylome, site-specific CpG and CH methylation, and transcriptomic signatures in the neonatal brain

Maternal e-cigarette exposure alters DNA methylome, site-specific CpG and CH methylation, and transcriptomic signatures in the neonatal brain

Abstract Maternal use of e-cigarette (e-cig) aerosols poses significant risks to fetal brain development, potentially increasing susceptibility to neurodevelopmental disorders in later life. However, the underlying mechanisms remain incompletely understood. This study aimed to understand the effects...

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Bibliographic Details
Main Authors: Andrew Walayat, Maryam Hosseini, Chirag Nepal, Yong Li, Wanqiu Chen, Zhong Chen, Xiaohui Huang, Xuesi M. Shao, Lubo Zhang, Charles Wang, Daliao Xiao
Format: Article
Language:English
Published: Nature Portfolio 2024-10-01
Series:Scientific Reports
Subjects:
Prenatal e-cigarette exposure
Neonatal brain
CpGs/CHs methylation
DNA methylome
Transcriptomic alteration
Online Access:https://doi.org/10.1038/s41598-024-75986-x
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https://doi.org/10.1038/s41598-024-75986-x

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