Genome-wide uH2A localization analysis highlights Bmi1-dependent deposition of the mark at repressed genes.

Polycomb group (PcG) proteins control organism development by regulating the expression of developmental genes. Transcriptional regulation by PcG proteins is achieved, at least partly, through the PRC2-mediated methylation on lysine 27 of histone H3 (H3K27) and PRC1-mediated ubiquitylation on lysine...

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Bibliographic Details
Main Authors: Eric M Kallin, Ru Cao, Raja Jothi, Kai Xia, Kairong Cui, Keji Zhao, Yi Zhang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-06-01
Series:PLoS Genetics
Online Access:https://journals.plos.org/plosgenetics/article/file?id=10.1371/journal.pgen.1000506&type=printable
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