Optimized CUT&RUN protocol for activated primary mouse B cells.

ChIP-seq has long been the standard for study of chromatin-protein interactions. However, development of a new technique, CUT&RUN, showed substantial advantages compared to ChIP-seq including higher quality signal while using substantially less sample. While a powerful technique, the original pr...

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Bibliographic Details
Main Authors: Stormy E Ruiz, Robert W Maul, Patricia J Gearhart
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2025-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0322139
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