A Computational Approach to Repurposing Natural Products for DprE1 Inhibition
This study aimed to investigate the potential of natural products (NPs) as inhibitors of decaprenylphosphoryl-D-ribose 2′-epimerase (DprE1), an enzyme crucial in Mycobacterium tuberculosis cell wall synthesis. Over 100 NPs were screened for anti-TB properties. Subsequently, the binding mechanism of...
Saved in:
| Main Authors: | , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wiley
2025-01-01
|
| Series: | Scientifica |
| Online Access: | http://dx.doi.org/10.1155/sci5/2105236 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|