Therapeutic hyperthermia promotes lipid export and HSP70/90 during machine perfusion of human livers

Therapeutic hyperthermia promotes lipid export and HSP70/90 during machine perfusion of human livers

Abstract Liver transplantation is the only curative option for end‐stage liver disease. Donor shortages necessitate the use of higher risk donor livers, including fatty livers, which are more susceptible to ischemia‐reperfusion injury. Machine perfusion has improved graft utilization and is typicall...

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Bibliographic Details
Main Authors: Adam M. Thorne, Yana Geng, Veerle A. Lantinga, Marieke Smit, Jan Albert Kuivenhoven, Robert J. Porte, Folkert Kuipers, Peter Olinga, Justina C. Wolters, Vincent E. deMeijer
Format: Article
Language:English
Published: Wiley 2025-05-01
Series:Physiological Reports
Subjects:
hyperthermia
lipids
liver
machine perfusion
proteomics
Online Access:https://doi.org/10.14814/phy2.70348
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https://doi.org/10.14814/phy2.70348

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