Comparison of the Genetic Alterations between Primary Colorectal Cancers and Their Corresponding Patient-Derived Xenograft Tissues

Patient-derived xenograft (PDX) models are useful tools for tumor biology research and testing the efficacy of candidate anticancer drugs targeting the druggable mutations identified in tumor tissue. However, it is still unknown how much of the genetic alterations identified in primary tumors are co...

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Bibliographic Details
Main Authors: Sang Mi Yu, Seung-Hyun Jung, Yeun-Jun Chung
Format: Article
Language:English
Published: BioMed Central 2018-06-01
Series:Genomics & Informatics
Subjects:
Online Access:http://genominfo.org/upload/pdf/gi-2018-16-2-30.pdf
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