Hematopoietic stem cell size heterogeneity is not linked to changes in stem cell potential of aged HSCs

Aging is associated with a decline in the function of hematopoietic stem cells (HSCs). This decline in HSC function results in reduced hematologic regenerative capacity and an increased incidence of hematologic disorders. In general, aged HSCs show on average an increase in cell size and a lower fre...

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Bibliographic Details
Main Authors: Mehmet Saçma, Ali Hageb, Alex Zadro, Tanja Schuster, Mona Vogel, Karina Eiwen, Vadim Sakk, Hartmut Geiger
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-05-01
Series:Frontiers in Aging
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Online Access:https://www.frontiersin.org/articles/10.3389/fragi.2025.1596565/full
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