Mapping Nanoscale‐To‐Single‐Cell Phosphoproteomic Landscape by Chip‐DIA

Mapping Nanoscale‐To‐Single‐Cell Phosphoproteomic Landscape by Chip‐DIA

Abstract Protein phosphorylation plays a crucial role in regulating disease phenotypes and serves as a key target for drug development. Mapping nanoscale‐to‐single‐cell samples can unravel the heterogeneity of cellular signaling events. However, it remains a formidable analytical challenge due to th...

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Bibliographic Details
Main Authors: Gul Muneer, Sofani Tafesse Gebreyesus, Ciao‐Syuan Chen, Tzu‐Tsung Lee, Fengchao Yu, Chih‐An Lin, Min‐Shu Hsieh, Alexey I. Nesvizhskii, Chao‐Chi Ho, Sung‐Liang Yu, Hsiung‐Lin Tu, Yu‐Ju Chen
Format: Article
Language:English
Published: Wiley 2025-01-01
Series:Advanced Science
Subjects:
library DIA
lung cancer
microfluidics
phosphorylation
single‐cell phosphoproteomics
Online Access:https://doi.org/10.1002/advs.202402421
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https://doi.org/10.1002/advs.202402421

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